Sr. Manager, Marketing & Commercial Excellence

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

The Senior Manager, Marketing & Commercial Excellence will be a critical member of the US Marketing and Commercial organization who will help build the future of Madrigal. This is truly a unique opportunity to make a difference for the betterment of patients living with MASH. This individual will ultimately be responsible for supporting and/or managing workstreams focused on operational systems, platforms, and processes to support Promotional Material Review (PRC), print operations, digital infrastructure, field communications, process improvement, budget, and more.

Core Responsibilities:

• Responsible for day-to-day promotional review committee (PRC) operations such as scheduling and facilitating PRC meetings and effectiveness, reinforcing PRC processes, managing Veeva workflows (submissions, QC, approvals, expirations, reporting), performing quality control checks, conducting PRC onboarding/training, etc.
• Support regulatory operations on promotional material submissions to FDA/OPDP (2253 and subpart H preclearance)
• Involvement with other critical operational workstreams may include (but not limited to), print vendor and fulfillment, Veeva CRM platform, budget management and field collaboration
• Support the implementation of existing and new systems, platforms, and processes to support cross-functional teams while proactively identifying opportunities to drive efficiencies and effectiveness as the business evolves
• Help elevate, oversee, and continuously improve the commercial operations function
• Effectively collaborate to ensure alignment and success with cross-functional partners including Medical, Regulatory, Legal, Compliance, Marketing, IT, Field Teams, Market Access, Agencies, Vendors, etc.
• Manage multiple vendor and agency partners to drive critical workstreams forward, ensure appropriate resource allocation and timely delivery within financial constraints

Key Job Requirements:

• Proactive, self-starter motivated by challenges and delivering results (business owner mindset)
• High learning agility and problem-solving skills with ability to multi-task across several projects
• Strong analytical skills to quickly diagnose problems and develop fit-for-purpose solutions
• Ability to work independently while also partnering with cross-functional teams
• Strong project management skills with proven success in delivering results
• Ability to execute and thrive in fast-paced environments filled with ambiguity
• Superb communication skills, both verbal and written
• Demonstrated expertise in managing Veeva PromoMats, Smartsheet, SharePoint and Microsoft Office
• Desire to professionally develop and gain more responsibilities resulting in greater impact
• Limited travel – up to 25% of the time (including weekends as needed)
• Required to be in office 3 days per week (Conshohocken, PA or Waltham, MA)

Education/Experience:

• Bachelor's Degree
• 7+ years of biopharmaceutical marketing and/or operations experience
• Must have direct experience with promotional review committee operations (Veeva Vault/ PromoMats)
• 2+ years of experience in project management
• Experience in smaller company (or team) environments is a plus

Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands.  As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $150,000 - $184,000 per year.  We comply with all applicable minimum wage laws.

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.  

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. 

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com. 

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. 

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. 

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. 

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.  

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to HR@madrigalpharma.com. 

Biopharmaceutical company focused on therapies for metabolic steatohepatitis (MASH) and liver diseases. Based in Conshohocken, PA.

madrigalpharma.com