Associate Scientist, Lentivirus Downstream Process Development

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

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About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
 

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
 

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for an Associate Scientist, Lentivirus Downstream Process Development in Spring House, PA.

Purpose:
The Associate Scientist will support the development, characterization, and optimization of lentiviral vector downstream purification processes, contributing to process scale‑up, regulatory readiness, and technology transfer to manufacturing.

You will be responsible for:

• Conduct small scale lentiviral vector production process development using material from mammalian cell culture. Purification techniques will include depth filtration, affinity and/or Ion exchange (IEX) chromatography, and tangential flow filtration (TFF), sterile filtration etc.
• Performing a range of viral vector process characterization studies to support process performance qualification (PPQ) and regulatory filing.
• Assist the process technical transfer to manufacturing site as needed
• Design, execute, analyze data and draft reports for studies
• Stay current with relevant literature and evaluate new emerging technologies in viral vector production, incorporating them into processes as appropriate
• Work in a team environment as well as individually to meet project timeline and objective.
• Ensure data integrity through accurate and timely data capture/entry into appropriate electronic systems

Qualifications / Requirements:
 

Education:

• Minimum of a Bachelor's degree in Biology, Biochemistry, Bioprocess Engineering, Virology, or a related scientific field is required
• Master’s degree is preferred
   

Required:

• Minimum 1 year of experience doing protein and/or viral vector purification
• Strong interpersonal skills, with the ability to closely collaborate with scientists and external teams
   

Preferred:

• Lentivirus/AAV downstream purification experience
• Experience with ÄKTA FPLC purification systems
• Experience with TFF systems
   

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. 
 

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers, internal employees contact AskGS to be directed to your accommodation resource.
 

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Global healthcare company spanning pharmaceuticals, medtech, and consumer health products. Headquartered in New Brunswick, NJ.

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