Director, Upstream MSAT & Process Development

Scholar Rock

Cambridge, MA Onsite Process Development Full-Time

About this role

Scholar Rock is a biopharmaceutical company that discovers, develops, and delivers life-changing therapies for people with serious diseases that have high unmet need. As a global leader in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins and named for the visual resemblance of a scholar rock to protein structures, the clinical-stage company is focused on advancing innovative treatments where protein growth factors are fundamental. Over the past decade, the company has created a pipeline with the potential to advance the standard of care for neuromuscular disease, cardiometabolic disorders, cancer, and other conditions where growth factor-targeted drugs can play a transformational role.

Scholar Rock is the only company to show clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). This commitment to unlocking fundamentally different therapeutic approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. By harnessing cutting-edge science in disease spaces that are historically under-addressed through traditional therapies, Scholar Rock works every day to create new possibilities for patients. Learn more about the company’s approach at ScholarRock.com and follow @ScholarRock and on LinkedIn.

Summary of Position:

We are seeking an experienced and strategic Director of Upstream MSAT and Process Development within Technical Operations (CMC) to lead our biologics upstream MSAT and process development function across early-stage, late-stage, and commercial programs. This role will support externally partnered GMP production of Scholar Rock’s clinical and commercial assets with deep manufacturing science and technology expertise. The candidate will also drive the design, scale-up, and technology transfer of drug substance processes—both internally and through a global network of CDMOs. The ideal candidate combines deep upstream technical knowledge, strong organizational leadership, and proven experience managing external collaborations and in-house teams. This role is critical to ensuring robust, scalable, processes that support clinical and commercial success.