Senior CRA

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

As a Senior Clinical Research Associate I at ICON, you will play a key role in the delivery of clinical trials by managing and monitoring investigator sites to ensure patient safety, data integrity, and compliance with protocol, ICH GCP, and regulatory requirements. You will act as the primary point of contact for assigned sites, driving high-quality study execution and fostering strong site relationships.

What You Will Do:

In this role you will be responsible for the end-to-end monitoring and oversight of clinical trial sites, from study start-up through close-out.

Key responsibilities include:

• Conduct site initiation, routine monitoring, and close-out visits (on-site and remote) in accordance with study plans and SOPs
• Ensure investigator site compliance with study protocols, ICH GCP, and applicable regulatory requirements
• Act as the primary contact for assigned sites, supporting site performance, enrollment, and issue resolution
• Identify site-level risks and implement corrective and preventive actions to ensure quality and compliance
• Review clinical data, including adverse events and serious adverse events, to ensure accuracy and patient safety
• Maintain high-quality monitoring documentation, including reports, trial master file records, and follow-up communications
• Collaborate with cross-functional teams to support study delivery, timelines, and database lock activities

Your Profile:

To succeed in this role, you will bring strong clinical monitoring expertise, a proactive mindset, and the ability to work independently while maintaining high standards of quality and compliance.

Required qualifications and experience:

• Degree in life sciences, nursing, pharmacy, or a related discipline
• Ideally, minimum 5 years of clinical research monitoring experience (oncology experience preferred)
• Strong knowledge of ICH GCP, FDA, and local regulatory requirements
• Experience managing investigator sites across the full clinical trial lifecycle
• Willingness to travel to sites in line with study requirements

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our careers site to read more about the benefits ICON offers.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.

Are you a current ICON Employee? Please click here to apply

Global contract research organization providing outsourced clinical development services. Headquartered in Dublin, Ireland.

iconplc.com