About this role
Who We Are:
At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.
What We Do:
Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)
About the Role:
Provides advanced technical expertise for life sciences facilities supporting research, clinical development, and regulated spaces. This role is accountable for the performance, reliability, and compliance of mission-critical facility systems and leads engineering strategies that ensure operational excellence in regulated environments. Leads complex, cross-functional engineering programs and initiatives that impact facility infrastructure, regulatory readiness, and long-term asset performance.The Principal Engineer serves as a key technical resource for infrastructure systems, including laboratory HVAC, process utilities, building automation systems, laboratory and automation equipment, and electrical distribution. This position supports infrastructure performance to enable scientific advancement, product development, and facility operations.
In partnership with Facilities, Research and Development, Quality, Validation, Environmental Health & Safety, and Information Technology, this role supports engineering initiatives that improve system reliability, regulatory readiness, and asset performance. Develops and advances engineering standards, best practices, and technical approaches for facilities infrastructure.
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Your Contributions (include, but are not limited to):
Leads engineering assessments and drives capital planning activities, including prioritization of infrastructure investments aligned with business and regulatory needs. Monitors performance, validation status, and compliance of critical systems, including certifications, HVAC qualification, process utilities, utility distribution networks, electrical systems, and environmental monitoring systems
Leads cross-functional collaboration with Facilities, R&D, Quality, Validation, EHS, and IT to define and implement infrastructure solutions. Develops and maintains maintenance strategies, corrective maintenance plans, contracts, and statements of work; supports updates to drawings and engineering specifications
Supports administration and continuous improvement of the Computerized Maintenance Management System (CMMS), including data integrity and system utilization
Leads execution of complex engineering projects from design through commissioning, ensuring alignment with GMP standards and lifecycle validation requirements. Leads technical evaluations and risk assessments of mission-critical infrastructure and determines mitigation strategies to reduce operational and regulatory risk. Provides technical support for FDA inspections and regulatory audits; ensures systems and documentation remain inspection ready
Participates in infrastructure-related investigations, root cause analysis, deviation resolution, and corrective and preventive actions
Provides technical leadership, coaching, and mentorship to engineers and facilities staff; may lead indirect or matrixed teams. Communicates system performance, risks, and project updates to management and cross-functional stakeholders
Other duties as assigned
Requirements:
High School Diploma and 10+ years of progressive engineering experience in life sciences, pharmaceutical, or biotechnology environments supporting critical infrastructure systems OR
Bachelor’s degree in mechanical, Electrical, Chemical, or related engineering discipline and 6 + years of progressive engineering experience in life sciences, pharmaceutical, or biotechnology environments supporting critical infrastructure systems
Equivalent combination of education and experience may be considered
Serves as a recognized subject matter expert and primary technical authority for facility infrastructure systems
Experience with HVAC systems, process utilities, electrical distribution systems, building automation systems, and laboratory systems
Experience with AutoCAD, Bluebeam, and other design and document review tools
Experience supporting infrastructure capital projects and system upgrades
Working knowledge of utility systems including chilled water, hot water, compressed air, vacuum
Strong analytical, organizational, and problem-solving skills
Requires strong understanding of engineering principles supporting laboratory and regulated environments, including HVAC systems, process utilities, electrical distribution, building automation systems, and laboratory systems
Demonstrated ability to influence technical decisions, drive alignment across functions, and lead initiatives without direct authority
Applies knowledge of how engineering functions integrate with Manufacturing, Quality, Validation, Environmental Health & Safety, and Facilities Operations.
Works on complex technical issues requiring evaluation of regulatory requirements, operational risk, and system performance
Uses structured problem-solving and analytical thinking to support system reliability and validated state
Acts as a technical resource for infrastructure-related issues and supports resolution of complex problems
Demonstrates understanding of FDA and GMP regulatory expectations related to facility systems, documentation, and change control
Collaborates cross-functionally to support infrastructure performance and compliance
Exercises sound judgment in managing systems that impact operations and compliance
Communicates technical information clearly to stakeholders
#LI-CL1
Neurocrine Biosciences is an EEO/Disability/Vets employer.
We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.
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The annual base salary we reasonably expect to pay is $132,700.00-$182,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 30% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.About Neurocrine Biosciences
Biopharmaceutical company developing therapies for neurological and endocrine disorders. Headquartered in San Diego, CA.
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