Jobs / Alnylam Pharmaceuticals / Cyber Defense Platforms Staff Engineer

Cyber Defense Platforms Staff Engineer

Alnylam Pharmaceuticals
US +1 more Engineering & Technology Full-time
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About this role

Own the deployment, configuration, administration, and lifecycle of defense platforms including SIEM, SOAR, EDR, DLP, email security, and phishing Define the platform roadmap: evaluate, deploy, integrate, and rationalize security technologies to maximize defensive coverage and operational efficiency Engineer and maintain security data pipelines across the enterprise: log source onboarding, normalization, enrichment, retention, and cost management Own the detection content lifecycle end-to-end: development, testing, tuning, versioning, and retirement of rules and analytics across all platforms Establish detection-as-code practices, including version control, peer review, CI/CD deployment, and automated validation of content Map detection coverage to MITRE ATT&CK, identify gaps, and partner with threat intel, IR, and offensive security to convert findings into durable detections Design and build SOAR playbooks and workflow automation that reduce manual analyst effort and accelerate triage and response, including automated handling of user-reported phishing Build internal tooling, integrations, and APIs that connect security platforms to each other and to enterprise systems Set the standards for how Cyber Defense builds, deploys, and operates its technology, and serve as the technical authority for the defense technology domain Lead cross-functional technical initiatives across IT, infrastructure, and engineering teams, and mentor engineers and analysts across the broader team 8+ years of progressive experience in security engineering, security operations, or detection engineering, with demonstrated ownership of defense and security platforms Deep hands-on expertise architecting and administering: SIEM, SOAR, EDR, DLP, or email security and anti-phishing platforms Strong software engineering skills in a language commonly used for security automation (e.g., Python, Go, PowerShell), with experience building production-quality integrations and tooling Proven experience building and managing detection content at scale, measured against frameworks like MITRE ATT&CK Track record of delivering measurable operational improvements through automation, such as reduced response times or expanded capacity without added headcount Ability to operate autonomously in a build-from-zero environment and drive technical work across teams you don't manage Experience standing up or modernizing a security operations stack (SIEM migration, SOAR implementation, EDR rollout) from early maturity Cloud security experience, particularly AWS-native security services Experience in regulated industries (pharma, biotech, healthcare, financial services) Relevant certifications (e.g., GIAC GCDA/GDAT/GCIA, CISSP) or equivalent expertise

About Alnylam Pharmaceuticals

Biopharmaceutical company pioneering RNA interference (RNAi) therapeutics for rare genetic, cardiometabolic, and CNS diseases. Headquartered in Cambridge, MA.

alnylam.com

Job Details
PostedAug 25, 2026
LocationUS +1 more
DepartmentEngineering & Technology
EmploymentFull-time
SenioritySenior
CountryUnited States
About the company
Alnylam Pharmaceuticals
Biopharmaceutical company pioneering RNA interference (RNAi) therapeutics for rare genetic, cardiometabolic, and CNS diseases. Headquartered in Cambridge, MA.
View all 97 open jobs at Alnylam Pharmaceuticals
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Hiring locations: United States (89), United Kingdom (3), Germany (2)
Salary benchmark for Engineering & Technology roles in United States: median 142,250 โ€“ 209,400 USD ยท based on 18 similar roles