Associate / Scientist - Cardiometabolic Research

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. 

The Cardiometabolic research (CMR) of Eli Lilly and Company focuses on the discovery of biological, small molecule and genetic therapeutics for the treatment of diabetes, obesity and associated complications. 

We are seeking a motivated scientist to join a highly collaborative drug discovery and development team in the Cardiovascular and Renal research group in Indianapolis. The successful candidate will apply strong molecular and cellular laboratory skills to support research efforts and pipeline projects focused on vascular inflammation. This individual will contribute to the development, execution, and optimization of in vitro biochemical and cellular assays and will work closely with scientists across teams to advance project and department goals.

Key responsibilities include: 

• Design and implement in vitro biochemical and cell-based experiments to support preclinical characterization and evaluation of relevant targets and pathways using pharmacological agents, including small molecules, antibodies, peptides, and siRNAs.
• Perform molecular and biochemical assessments on samples from tissues and cells including RNA/DNA isolation and analysis, gene and protein expression analyses, and other analytical techniques.
• Perform gene expression manipulations including silencing, transient transfections, and stable cell line generation.
• Perform cell-based assays including cytokine stimulation, immunophenotypic characterization by flow cytometry, and related cellular analyses.
• Demonstrate the ability to work effectively both independently and within cross-functional project teams, with a strong sense of ownership and accountability.
• Show adaptability by learning new techniques, developing biological understanding, and contributing to a data-driven research environment.
• Maintain accurate records, analyze data, and communicate results in written and oral formats while working in compliance with Lilly Research policies and required training expectations.

Minimum qualifications: 

• Bachelor’s degree in biology, molecular biology, biochemistry, or a related field
• 1 year in vitro experience in industry, academia or related field

• Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

Additional Skills/Preferences 

• A background in biology, cell/molecular biology and metabolic disease is a plus 
• Masters degree in biology, molecular biology, biochemistry or related field
• Hands-on experience with gene editing or gene expression analysis methods, including gDNA/RNA isolation, qPCR, ddPCR, and protein expression analysis such as western blot, JESS, ELISA, or MSD, along with flow cytometry is preferred.
• Hands-on experience in cellular and molecular biology techniques and in vitro assay execution gained through academic research, internships, or industry experience
• Experience with complex cell culture systems, primary culture, or co-culture
• Proficiency in cell biology techniques including cell culture, transfection, FACS, and cell-based assays
• Experience with various assay detection technologies (fluorescence, luminescence, alpha-screen)
• Willingness to learn and help implement new technologies and laboratory methods.
• Demonstrated ability to work collaboratively on cross-functional teams and research projects.

• Strong communication skills and experience presenting data in a team environment 
• Ability to work independently as well as part of a results-oriented research team; highly organized with significant attention to detail.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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